Howard (Hao) Wu, PhD has almost 20 years’ experience in gene editing technology and new drug discovery. He is specialized in overseeing R&D programs, new lab and research team set up in the biotech start-ups.

Dr. Wu is the co-founder and CEO/CSO of Full Circles Therapeutics, where he is dedicated to developing curative gene editing based gene/cell therapy. He is responsible for generating revenue through collaboration with MNC and biotech partners. Before founding Full Circles Therapeutics, Dr. Wu was leading multiple discovery biology programs and disease prioritization in the genetic disease space at Fulcrum Therapeutics Inc. (NASDAQ:FULC), a Cambridge small molecule drug discovery biotech company. He had been with the company through the full development phases starting from the start-up, expansion, until post-IPO development, during which he led a cross-functional team for portfolio disease selection and prioritization of multiple disease programs including neuromuscular disease, cardiac disease, hematological and metabolic diseases, including two major partnership collaborations with MyoKardia and Acceleron.

Before joining Fulcrum, Dr. Wu was a senior research fellow at Whitehead institute, MIT. His research focused on neurological disorders utilizing a combination of CRISPR/Cas9 mediated genomic and epigenomic editing technology and stem cell technology. He did his PhD in Biochemistry and Structural Biology at Hongkong University of Science and Technology (HKUST) and Bachelor’s degree in Chemistry from Fudan University before he did his postdoctoral research at Johns Hopkins University School of Medicine and Howard Hughes Medical Institute. Dr. Wu has more than 30 journal publications, patents, and research and industry grants. For his work, he has received fellowship award from human frontier science program (HSFP) and NARSAD young investigator award. He was also awarded the Alfred Blalock Young Investigator Award from JHMI and President’s award from Whitehead Institute, MIT.

Founders are everywhere, but resources aren’t.

That’s a shame, because the next big idea could come from anywhere.


The Massachusetts Founder Network aims to bridge the gap, giving startup founders equitable access to resources that will help their companies grow.


We support MA founders no matter where they come from, their company’s stage, or their business sector. We want to democratize access to the resources that will help them accelerate—and excel. All founders are welcome to find resources and community at MFN while creating connections, expanding their networks, and learning from one another.

About MFN

The Massachusetts Founders Network is a central hub for all things startups, fostering innovation and collaboration across the state. MFN offers valuable networking, resources, mentorship, and community for startup founders in Massachusetts. 


MFN is produced by Lever, a startup accelerator based in North Adams. Our work is supported by funding from and collaboration with the Massachusetts Technology Collaborative, based in Westborough.


We’ve been advising and connecting with entrepreneurs for years, and we’re using that knowledge and network to launch something new, with the help of an advisory board of successful founders and major players in the startup ecosystem. 

We plan to launch the Massachusetts Founders Network in summer 2023. Sign up for our newsletter to get alerts about our launch, new features, and MFN events!